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Table 2 Patient sputum and nasal swab cultivation report alongside bacterial 16S rRNA gene sequencing results

From: Longitudinal analysis of sinus microbiota post endoscopic surgery in patients with cystic fibrosis and chronic rhinosinusitis: a pilot study

Patient Collection timepointb Sputum sample Bacterial 16S rRNA sequencing Nasal swab Antimicrobial resistance
P01 Baseline Staphylococcus aureus
Othera 		Enterobacteriaceae, Enterobacter, Staphylococcus, Corynebacterium Other None assessed
  6 Staphylococcus aureus, Morganella morganii, Enterobacter cloacae
Other 		Enterobacteriaceae, Enterobacter, Staphylococcus Enterobacter cloacae
Other 		Amoxycillin, Amoxycillin + clavulanate, cefuroxime
  13 Staphylococcus aureus, Chryseobacterium indologenes
Other 		Enterobacteriaceae, Enterobacter, Staphylococcus, Corynebacterium Staphylococcus aureus
Other 		Penicillin
  15 Staphylococcus aureus, mould
Other 		Enterobacteriaceae, Enterobacter, Staphylococcus Enterobacter cloacae, Staphylococcus aureus Amoxycillin, cefuroxime, amoxycillin + clavulanate, penicillin
  18 Staphylococcus aureus, mould
Other 		Enterobacteriaceae, Enterobacter, Staphylococcus Staphylococcus aureus, Enterobacter cloacae Penicillin, erythromycin, amoxycillin, cefuroxime, amoxycillin + clavulanate
P02 Baseline Pseudomonas aeruginosa
Other 		Staphylococcus, Pseudomonas Pseudomonas aeruginosa
Other 		Gentamicin
  2 Pseudomonas aeruginosa
Other 		Staphylococcus, Pseudomonas Other –
  6 – Pseudomonas – –
  11 Pseudomonas aeruginosa
Other 		Pseudomonas, Corynebacterium Pseudomonas aeruginosa Gentamicin
P03 Baseline Staphylococcus aureus Staphylococcus Staphylococcus aureus Penicillin, flucloxacillin
  3 – Staphylococcus, Corynebacterium – –
  6 Staphylococcus aureus
Other 		Staphylococcus, Enterobacter Staphylococcus aureus Penicillin, flucloxacillin
  12 Staphylococcus aureus
Other 		Staphylococcus, Enterobacteriaceae Staphylococcus aureus Penicillin, flucloxacillin
P04 Baseline Data not collectedc Pseudomonas, Staphylococcus Pseudomonas aeruginosa, Aspergillus fumigatus
Other 		Gentamicin, amikacin, ciprofloxacin
  3 – Pseudomonas Pseudomonas aeruginosa Gentamicin, ciprofloxacin
  6 – Pseudomonas Pseudomonas aeruginosa
Other 		Ceftazidime, gentamicin
  7 – Pseudomonas, Staphylococcus, Corynebacterium Pseudomonas aeruginosa, Fusarium solani complex
Other 		Gentamicin, amikacin, ciprofloxacin
  11   Pseudomonas, Staphylococcus Pseudomonas aeruginosa
Other 		Gentamicin
  1. In vitro antimicrobial resistance is noted only for nasal swab isolates. Results from left and right middle meatus swabs for molecular techniques are combined. In vitro antimicrobial resistance profiles from nasal swab bacteria are noted
  2. a‘Other’ refers to growth of bacterial colonies that were not considered clinically relevant. This includes mixed oropharyngeal bacteria, mixed Gram-positive and Gram-negative colonies, commensal flora or skin flora. These colonies were not further isolated or identified
  3. bCollection timepoint is given as months since baseline collection
  4. cSputum samples were not collected from this patient. Analysis of patient records revealed that prior to lung transplantation in 2012 the dominant organisms recovered from sputum were Pseudomonas aeruginosa and Aspergillus fumigatus. Sputum collected post lung transplantation, but prior to this study, cultured Pseudomonas aeruginosa
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Respiratory Research

ISSN: 1465-993X

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