Fig. 3

Step-down of asthma background medication. aAdditional controller medications can be changed or their doses can be up-titrated or down-titrated at the discretion of the investigator. bIf the patient is not taking a combination of ICS/LABA and is taking a separate ICS and additional controller medication(s), reduce only the dose of ICS and maintain the same dose of the additional controller medication(s). ICS inhaled corticosteroid, LABA long-acting β2-agonist, OCS oral corticosteroid, PRN prescribed-as-needed, SABA short-acting β2-agonist